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AuthorWinter, Julianedc.contributor.author
Date of accession2016-03-15T06:24:44Zdc.date.accessioned
Available in OPARU since2016-03-15T06:24:44Zdc.date.available
Year of creation2009dc.date.created
AbstractWe prospectively evaluated a real-time polymerase chain reaction (PCR) approach for the rapid diagnosis of Staphylococcus spec ies and Staphylococcus aureus bacteraemia as well as candidaemia presence in 490 blood samples of 208 immunocompromised patients. Compared to blood culture (BC), the diagnostic sensitivity and specificity of the Staphylococcus species PCR were 60.0 and 95.7 %, of the Staphylococcus aureus PCR 60.0 and 99.2 % and of the Candida PCR 28.6 and 95.5 %. Although standard BC diagnostics appear to remain indispensable for the detection of all cases of bacteraemia and candidaemia, the PCR assay is an alternative or additional tool for the diagnosis of sepsis, mainly if the patient is under antibiotic or antifungal therapy. Furthermore, in many cases, it allows earlier diagnosis than BC diagnostics, especially in Candida infections.dc.description.abstract
Languagededc.language.iso
PublisherUniversität Ulmdc.publisher
LicenseStandard (Fassung vom 01.10.2008)dc.rights
Link to license texthttps://oparu.uni-ulm.de/xmlui/license_v2dc.rights.uri
KeywordImmunsupprimierte Patientendc.subject
KeywordPCRdc.subject
KeywordSepsisdiagnostikdc.subject
Dewey Decimal GroupDDC 610 / Medicine & healthdc.subject.ddc
MeSHImmunosuppressiondc.subject.mesh
TitleEntwicklung und klinische Evaluation eines molekularen Schnellverfahrens zur Sepsisdiagnostik bei immunsupprimierten Patientendc.title
Resource typeDissertationdc.type
DOIhttp://dx.doi.org/10.18725/OPARU-2099dc.identifier.doi
PPN640659527dc.identifier.ppn
URNhttp://nbn-resolving.de/urn:nbn:de:bsz:289-vts-74072dc.identifier.urn
GNDImmunsuppressiondc.subject.gnd
GNDPolymerase-Kettenreaktiondc.subject.gnd
FacultyMedizinische Fakultätuulm.affiliationGeneral
Date of activation2010-11-10T14:09:02Zuulm.freischaltungVTS
Peer reviewneinuulm.peerReview
Shelfmark print versionZ: J-H 13.803; W: W-H 12.272uulm.shelfmark
DCMI TypeTextuulm.typeDCMI
VTS ID7407uulm.vtsID
CategoryPublikationenuulm.category
Bibliographyuulmuulm.bibliographie


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