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AuthorSchoch, Michaeladc.contributor.author
Date of accession2016-03-15T06:24:38Zdc.date.accessioned
Available in OPARU since2016-03-15T06:24:38Zdc.date.available
Year of creation2009dc.date.created
AbstractResults: 322 [11C]-Choline PET/CT examinations were performed after a mean period after primary therapy of 35 mos. (range: 1-720 mos.). 76% (246/322) of the hormonnaive pts. underwent [11C]-Choline PET/CT, in 24% (76/322) PET/CT was performed during antiandrogen- therapy. PET positive results are seen in 71% (229/322) at a median PSA 5.9 ng/ml (range: 0-444 ng/ml), at a mean PSA of 1.8 ng/ml (range: 0.017-16.8 ng/ml) in 29% (93/322) PET showed a negative result. Tumour manifestations are seen in PET in group A (operative intention) in 65% (135/193), in group B (pts. after brachytherapy or radiotherapy) in 80% (20/25), in group C (pts. after antiandrogen-therapy) in 81% (84/104). Multiple tumour manifestations were detected in 29% only, isolated relapse was found in 71% (163/229). Isolated local relapse was demarked in 56% (129/229; in group A 30% [58 pts.], isolated pelvine lymph nodes in 14% (34/229, in group A 16% [30 pts.], in group B 8% [2 pts.]). Only in 7% (16/229) osseous metastases were observed. Conclusion: [11C]-Choline PET/CT as a single-step exam is an accurate imaging modality to identify the location in patients with recurrent diseases. In case of rising PSA after therapy a discrimination between local and systemic progression can be taken by using [11C]-Choline PET/CT. Therefore, in patients with prostate cancer relapse after therapy with curative intention [11C]-Choline PET/CT seems to be a useful diagnostic tool to select patients suitable for salvage radiotherapy.dc.description.abstract
Languagededc.language.iso
PublisherUniversität Ulmdc.publisher
LicenseStandard (Fassung vom 01.10.2008)dc.rights
Link to license texthttps://oparu.uni-ulm.de/xmlui/license_v2dc.rights.uri
Keyword[11C]-Choline PET/CTdc.subject
KeywordProstate cancer after therapy with curative intentiondc.subject
Dewey Decimal GroupDDC 610 / Medicine & healthdc.subject.ddc
MeSHProstatic neoplasms. Therapydc.subject.mesh
TitleStellenwert der 11C-Cholin-PET/CT in der onkologischen Nachsorge bei Patienten mit Prostatakarzinom nach erfolgter Primärtherapiedc.title
Resource typeDissertationdc.type
DOIhttp://dx.doi.org/10.18725/OPARU-2063dc.identifier.doi
PPN630901090dc.identifier.ppn
URNhttp://nbn-resolving.de/urn:nbn:de:bsz:289-vts-73145dc.identifier.urn
FacultyMedizinische Fakultätuulm.affiliationGeneral
Date of activation2010-07-01T11:07:37Zuulm.freischaltungVTS
Peer reviewneinuulm.peerReview
Shelfmark print versionZ: J-H 13.716; W: W-H 12.162uulm.shelfmark
DCMI TypeTextuulm.typeDCMI
VTS ID7314uulm.vtsID
CategoryPublikationenuulm.category
Bibliographyuulmuulm.bibliographie


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