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AuthorWiedemann, Michaeldc.contributor.author
Date of accession2016-03-15T06:24:34Zdc.date.accessioned
Available in OPARU since2016-03-15T06:24:34Zdc.date.available
Year of creation2008dc.date.created
AbstractBACKGROUND: There is a rapid growth in evidence with regard to a possible link between periodontal disease and several systemic diseases. Periodontal disease is postulated to be the major reason of tooth loss in adults; inflammation is one of its components. Inflammatory processes are also involved in preterm/premature birth, diabetes mellitus as well as cardiovascular disease (CVD). METHODS: On the basis of a systematic literature research (until December 2007) and a study evaluation according to current evidence criteria, the task was to reliably examine if the accumulated common occurrence of periodontal disease and preterm birth, diabetes mellitus or cardiovascular disease is a simple coincidence or a causal relation. RESULTS: Periodontal disease is highly prevalent and affects at least 20 % of the worldwide population. The most important risk factor for periodontal disease as well as for CVD (and diabetes mellitus) is age. Periodontal disease frequently occurs in patients with preterm birth, diabetes mellitus or CVD. But it is definitely not a proven cause of these diseases. Periodontal treatment in pregnancy does not reduce the incidence of preterm birth. Periodontal treatment does not improve the glycaemic control and has no clinically important benefit for patients with diabetes. The treatment of periodontal disease has no influence on the occurrence and severity of cardiovascular events. CONCLUSION: The effects of periodontal treatment on tooth loss as well as the impact on preterm birth, diabetes mellitus or cardiovascular disease have to be analysed reliably. Experts agree that future studies should aim at important clinical endpoints. Large multicentre randomised controlled trials (RCTs) are needed to investigate whether the treatment of periodontal disease has an effect on preterm birth, diabetes mellitus or cardiovascular disease. Clinical decisions for periodontal treatment need reliable evidence-based investigations and results.dc.description.abstract
Languagededc.language.iso
PublisherUniversität Ulmdc.publisher
LicenseStandard (Fassung vom 01.10.2008)dc.rights
Link to license texthttps://oparu.uni-ulm.de/xmlui/license_v2dc.rights.uri
KeywordCVDdc.subject
KeywordHerzkreislauferkrankungdc.subject
KeywordPreterm birthdc.subject
Dewey Decimal GroupDDC 610 / Medicine & healthdc.subject.ddc
MeSHCardiovascular diseasesdc.subject.mesh
MeSHPeriodontal diseasesdc.subject.mesh
MeSHPremature birthdc.subject.mesh
TitleAbgesichertes Wissen zur Assoziation der Parodontitis mit Frühgeburt, Herzkreislauferkrankung und Diabetes mellitusdc.title
Resource typeDissertationdc.type
DOIhttp://dx.doi.org/10.18725/OPARU-2040dc.identifier.doi
PPN625118189dc.identifier.ppn
URNhttp://nbn-resolving.de/urn:nbn:de:bsz:289-vts-72590dc.identifier.urn
GNDDiabetes mellitusdc.subject.gnd
GNDFrühgeburtdc.subject.gnd
GNDParodontitisdc.subject.gnd
GNDSchwangerschaftdc.subject.gnd
FacultyMedizinische Fakultätuulm.affiliationGeneral
Date of activation2010-04-21T15:46:56Zuulm.freischaltungVTS
Peer reviewneinuulm.peerReview
Shelfmark print versionZ: J-H 13.105; W: W-H 11.554uulm.shelfmark
DCMI TypeTextuulm.typeDCMI
VTS-ID7259uulm.vtsID
CategoryPublikationenuulm.category
University Bibliographyjauulm.unibibliographie


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