Retinoic acid worsens ATG10-dependent autophagy impairment in TBK1-mutant hiPSC-derived motoneurons through SQSTM1/p62 accumulation

Erstveröffentlichung
2019
Authors
Catanese, Alberto
Heuvel, Florian Olde
Mulaw, Medhanie
Demestre, Maria
Higelin, Julia
et al.
Wissenschaftlicher Artikel


Published in
Autophagy ; 15 (2019), 10. - S. 1719-1737. - ISSN 1554-8627. - eISSN 1554-8635
Link to publication
https://dx.doi.org/10.1080/15548627.2019.1589257
Faculties
Medizinische Fakultät
Institutions
Institut für Anatomie und Zellbiologie
International Graduate School in Molecular Medicine Ulm (IGradU)
UKU. Klinik für Neurologie
UKU. Institut für Experimentelle Tumorforschung
UKU. Institut für Humangenetik
EU Project uulm
EURO-MOTOR / European multidisciplinary ALS network identification to cure motor neuron degeneration / EC / FP7 / 259867
Subject headings
[Free subject headings]: ALS | autophagy | hiPSC | motoneurons | TBK1 | PLURIPOTENT STEM-CELLS | UP-REGULATION | FRONTOTEMPORAL DEMENTIA | SELECTIVE AUTOPHAGY | PROMOTES AUTOPHAGY | TBK1 MUTATIONS | LIFE-SPAN | PROTEIN | P62/SQSTM1 | activation
[DDC subject group]: DDC 570 / Life sciences | DDC 610 / Medicine & health
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