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AuthorSharma, Sonudc.contributor.author
Date of accession2016-03-15T06:24:23Zdc.date.accessioned
Available in OPARU since2016-03-15T06:24:23Zdc.date.available
Year of creation2009dc.date.created
AbstractMolecular imaging by MR is challenging due to the fact that molecular targets are often present in very small numbers. Therefore, the high concentration of contrast agent necessary for detection, severely limits the application of MRI for monitoring molecular processes in vivo. As a result, improved imaging strategies and/or targeted molecular imaging contrast agents with high payload are needed. To achieve the goal of targeted molecular imaging for plaque characterization in future, the objectives of this thesis was to develop and test the potential use of polymeric vehicles (in chemical and biological environment) which can carry high payload of contrast agents to targeted site and serve as potential candidate for targeted molecular imaging. Another aspect was calcium quantification (present in plaque) by MRI using UTE sequence. This in future will help to improve the differentiation between signal losses generated by iron based contrast agents and signal loss due to presence of calcium in plaque.dc.description.abstract
Languageendc.language.iso
PublisherUniversität Ulmdc.publisher
LicenseStandard (Fassung vom 01.10.2008)dc.rights
Link to license texthttps://oparu.uni-ulm.de/xmlui/license_v2dc.rights.uri
KeywordContrast agentsdc.subject
KeywordInverse miniemulsiondc.subject
KeywordRelaxivitydc.subject
KeywordUltra short echo-time imagingdc.subject
Dewey Decimal GroupDDC 610 / Medicine & healthdc.subject.ddc
MeSHContrast mediadc.subject.mesh
MeSHMagnetic resonance imagingdc.subject.mesh
MeSHMagnetic resonance imaging, dentaldc.subject.mesh
TitleMRI studies of Gadolinium based contrast agents loaded nanocapsules and iron loaded nanoparticles in chemical and biological environmentdc.title
Resource typeDissertationdc.type
DOIhttp://dx.doi.org/10.18725/OPARU-1981dc.identifier.doi
PPN613931920dc.identifier.ppn
URNhttp://nbn-resolving.de/urn:nbn:de:bsz:289-vts-71168dc.identifier.urn
GNDNMR-Tomographiedc.subject.gnd
FacultyMedizinische Fakultätuulm.affiliationGeneral
Date of activation2009-11-23T09:40:38Zuulm.freischaltungVTS
Peer reviewneinuulm.peerReview
Shelfmark print versionZ: J-H 13.500; W: W-H 11.925uulm.shelfmark
DCMI TypeTextuulm.typeDCMI
VTS ID7116uulm.vtsID
CategoryPublikationenuulm.category
Bibliographyuulmuulm.bibliographie


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