A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies

Erstveröffentlichung

2019

Authors

Boettcher, Steffen

Miller, Peter G.

Sharma, Rohan

McConkey, Marie

Leventhal, Matthew

et al.

Wissenschaftlicher Artikel

Published in

Science ; 365 (2019), 6453. - S. 599+. - ISSN 0036-8075. - eISSN 1095-9203

Link to publication

https://dx.doi.org/10.1126/science.aax3649

Institutions

UKU. Klinik für Innere Medizin III

Subject headings

[Free subject headings]: MUTANT P53 | CLONAL HEMATOPOIESIS | SOMATIC MUTATIONS | POINT MUTATIONS | GENE ONTOLOGY | K562 CELLS | BCR-ABL | GAIN | CANCER | EXPRESSION
[DDC subject group]: DDC 570 / Life sciences | DDC 610 / Medicine & health

Metadata

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