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AuthorTütüncü, Erhandc.contributor.author
AuthorNägele, Markusdc.contributor.author
AuthorBecker, Steffendc.contributor.author
AuthorFischer, Marcdc.contributor.author
AuthorKoeth, Johannesdc.contributor.author
AuthorWolf, Christiandc.contributor.author
AuthorKöstler, Stefandc.contributor.author
AuthorRibitsch, Volkerdc.contributor.author
AuthorTeuber, Andreadc.contributor.author
AuthorGröger, Michaeldc.contributor.author
AuthorKress, Sandradc.contributor.author
AuthorWepler, Martindc.contributor.author
AuthorWachter, Ulrichdc.contributor.author
AuthorVogt, Josefdc.contributor.author
AuthorRadermacher, Peterdc.contributor.author
AuthorMizaikoff, Borisdc.contributor.author
Date of accession2019-09-17T09:34:50Zdc.date.accessioned
Available in OPARU since2019-09-17T09:34:50Zdc.date.available
Date of first publication2018-08-03dc.date.issued
AbstractA multiparameter gas sensor based on distributed feedback interband cascade lasers emitting at 4.35 μm and ultrafast electro-spun luminescence oxygen sensors has been developed for the quantification and continuous monitoring of 13CO2/12CO2 isotopic ratio changes and oxygen in exhaled mouse breath samples. Mid-infrared absorption spectra for quantitatively monitoring the enrichment of 13CO2 levels were recorded in a miniaturized dual-channel substrate-integrated hollow waveguide using balanced ratiometric detection, whereas luminescence quenching was used for synchronously detecting exhaled oxygen levels. Allan variance analysis verified a CO2 measurement precision of 1.6‰ during a 480 s integration time. Routine online monitoring of exhaled mouse breath was performed in 14 mechanically ventilated and instrumented mice and demonstrated the feasibility of online isotope-selective exhaled breath analysis within microliters of probed gas samples using the reported combined sensor platform.dc.description.abstract
Languageen_USdc.language.iso
PublisherUniversität Ulmdc.publisher
LicenseStandard (ohne Print-on-Demand)dc.rights
Link to license texthttps://oparu.uni-ulm.de/xmlui/license_opod_v1dc.rights.uri
Keywordbreath analysis,dc.subject
Keywordelectrospun polymer nanofiberdc.subject
Keywordinterband cascade laserdc.subject
Keywordisotope enrichmentdc.subject
Keywordsubstrate integrated hollow waveguidedc.subject
Dewey Decimal GroupDDC 540 / Chemistry & allied sciencesdc.subject.ddc
LCSHBreath testsdc.subject.lcsh
LCSHIsotope separationdc.subject.lcsh
LCSHSubstrate integrated waveguidesdc.subject.lcsh
TitleAdvanced photonic sensors based on interband cascade lasers for real-time mouse breath analysisdc.title
Resource typeWissenschaftlicher Artikeldc.type
VersionacceptedVersiondc.description.version
DOIhttp://dx.doi.org/10.18725/OPARU-18980dc.identifier.doi
URNhttp://nbn-resolving.de/urn:nbn:de:bsz:289-oparu-19037-6dc.identifier.urn
GNDIsotopdc.subject.gnd
GNDHohlleiterdc.subject.gnd
GNDWellenleiterdc.subject.gnd
FacultyFakultät für Naturwissenschaftenuulm.affiliationGeneral
InstitutionInstitut für Analytische und Bioanalytische Chemieuulm.affiliationSpecific
InstitutionUKU. Institut für Anästhesiologische Pathophysiologie und Verfahrensentwicklunguulm.affiliationSpecific
Peer reviewjauulm.peerReview
DCMI TypeTextuulm.typeDCMI
CategoryPublikationenuulm.category
DOI of original publication10.1021/acssensors.8b00477dc.relation1.doi
Source - Title of sourceACS Sensorssource.title
Source - Place of publicationACS Publicationssource.publisher
Source - Volume3source.volume
Source - Issue9source.issue
Source - Year2018source.year
Source - From page1743source.fromPage
Source - To page1749source.toPage
Source - ISSN2379-3694source.identifier.issn
EU projectTROPSENSE / Development of a non-invassive breath test for early diagnosis of tropical diseases / EC / H2020 / 645758uulm.projectEU
Fundingproject APOSEMA (German BMBF via M-Era.net program)uulm.funding
University Bibliographyjauulm.unibibliographie


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