Implementation and evaluation of two distinct electronic motion detection devices for the assessment of abnormal movements in Huntington's disease

Abstract

Huntington’s Disease (HD) is a severe neurodegenerative disorder in which the impairment of voluntary movement causes significant functional disability. Clinical assessment of motor dysfunction currently relies on semiquantitative rating scales, which are time consuming and susceptible to subjective errors. This thesis presents a study to determine if capturing two simple movements (fingertapping and pro/supination) with electronic motion detection software on a handheld device is useful in assessing abnormal movements in HD and possibly other neurodegenerative diseases.