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AuthorKulaksiz, Muratdc.contributor.author
Date of accession2016-03-14T15:23:06Zdc.date.accessioned
Available in OPARU since2016-03-14T15:23:06Zdc.date.available
Year of creation2007dc.date.created
AbstractWe investigated the prevalence of Helicobacter pylori infection in a large group of women to determine whether there was an association of current infection status with Lewis blood group antigen A and B phenotype. METHODS: Between November 2000 and November 2001, mothers were recruited after delivery of their offspring at the Department of Gynecology and Obstetrics at the University of Ulm, Ulm, Germany. The H. pylori infection status of the women was determined by 13C urea breath test. Their Lewis A and Lewis B phenotype was determined using standard laboratory techniques. RESULTS: In total, 22.2 % of the 712 women included in the study (mean age 30.7 years) had a current H. pylori infection. The prevalence of infection varied from 15.5 % in women of German nationality to 75.0 % in women of Turkish nationality (p < .001). Most women (68.1 %) had a Le(a-b+) phenotype. The prevalence of H. pylori infection in women with Le(a-b+) phenotypes was lower than in other women (p = .02). In multivariate analysis, the odds ratio (OR) for a current H. pylori infection given Le(a-b+) was 0.56 [95 % confidence interval (CI) 0.33 - 0.95] compared to women with Le(a-b-). CONCLUSION: Le(a-b+) blood group phenotype in combination with secretor status may hinder colonization of H. pylori in the population studied.dc.description.abstract
Languagededc.language.iso
PublisherUniversität Ulmdc.publisher
LicenseStandard (Fassung vom 01.10.2008)dc.rights
Link to license texthttps://oparu.uni-ulm.de/xmlui/license_v2dc.rights.uri
Dewey Decimal GroupDDC 610 / Medicine & healthdc.subject.ddc
MeSHDisinfectiondc.subject.mesh
MeSHHelicobacter pyloridc.subject.mesh
MeSHLewis blood-group systemdc.subject.mesh
TitleDie Bedeutung der Blutgruppenantigene Lewis A und Lewis B für die Infektion mit Helicobacter-pyloridc.title
Resource typeDissertationdc.type
DOIhttp://dx.doi.org/10.18725/OPARU-1595dc.identifier.doi
PPN1651365865dc.identifier.ppn
URNhttp://nbn-resolving.de/urn:nbn:de:bsz:289-vts-68086dc.identifier.urn
GNDBlutgruppenantigendc.subject.gnd
FacultyMedizinische Fakultätuulm.affiliationGeneral
Date of activation2009-05-15T18:01:21Zuulm.freischaltungVTS
Peer reviewneinuulm.peerReview
Shelfmark print versionZ: J-H 13.279; W: W-H 11.717uulm.shelfmark
DCMI TypeTextuulm.typeDCMI
VTS-ID6808uulm.vtsID
CategoryPublikationenuulm.category


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