Früherkennung kolorektaler Neoplasien mittels hochauflösender Videokoloskope bei deutschen Männern zwischen 40 und 59 Lebensjahren ohne Risikofaktoren
Vogelsang, Eva Franziska
LicenseStandard (Fassung vom 01.10.2008)
Prevalence data for colorectal neoplastic lesions for a German average-risk population 40 - 59 yrs. of age obtained from screening colonoscopy have not been published. A screening colonoscopy was offered to all male participants of a health assessment programme. By using high-resolution endoscopes an unexpectedly large number of neoplastic lesions in the colon even in a relatively young average-risk population was found. 47 % of the subjects 40 - 49 yrs. of age had polypoid lesions (20 % non-neoplastic lesions, 27 % neoplastic lesions including 3.2 % advanced lesions). In comparison to the subjects 50 - 59 yrs. of age (55 % polypoid lesions, 19 % non-neoplastic lesions, 36 % neoplastic lesions including 10.2 % advanced lesions) the difference between the two age groups was statistically significant. An exceptionally high rate of 27 % neoplastic lesions was detected in subjects at 40 - 49 yrs. of age. The question whether screening colonoscopy should therefore not only aim at detecting early colorectal cancer but also at identifying and removing precursor adenomas at younger ages clearly deserves further attention.
Subject HeadingsDickdarmadenom [GND]
Colorectal neoplasms [MeSH]