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AuthorKöpke, Michaeldc.contributor.author
Date of accession2016-03-14T15:21:24Zdc.date.accessioned
Available in OPARU since2016-03-14T15:21:24Zdc.date.available
Year of creation2009dc.date.created
AbstractClostridium ljungdahlii was metabolically engineered for the production of bulk chemical and next generation biofuel 1-butanol from synthesis gas by transformation with a plasmid harbouring the butanol synthesis genes from Clostridium acetobutylicum. Synthesis gas (a mixture of CO, CO2 and H2) can be easily produced by gasification of biomass or municipal waste. Thus, this process presents an alternative to conventional butanol fermentation (which uses corn or sugar as substrate and therefore competes with the food industry) and also chemical butanol production (which starts from propen obtained from non-renewable sources). To optimize the process, metagenomic libraries from environmental sources were screened for novel butanol dehydrogenases. Four respective enzymes could be identified and characterized in detail. Further studies on the metabolism of C. ljungdahlii revealed a new type of energy conservation in acetogenic bacteria. There are indications that Clostridium difficile might also belong to this group, as respective genes were found in the genome sequence and weak autotrophic growth occurred on a mixture of CO2 and H2.dc.description.abstract
Languagededc.language.iso
PublisherUniversität Ulmdc.publisher
LicenseStandard (Fassung vom 01.10.2008)dc.rights
Link to license texthttps://oparu.uni-ulm.de/xmlui/license_v2dc.rights.uri
KeywordAcetogenesisdc.subject
KeywordBiofueldc.subject
KeywordClostridium ljungdahliidc.subject
KeywordMetagenomicsdc.subject
KeywordWood-Ljungdahl pathwaydc.subject
Dewey Decimal GroupDDC 570 / Life sciencesdc.subject.ddc
LCSHAlcohol dehydrogenasedc.subject.lcsh
LCSHBiomass energydc.subject.lcsh
LCSHButanoldc.subject.lcsh
LCSHEnergy conservationdc.subject.lcsh
LCSHSynthesis gasdc.subject.lcsh
MeSHMetabolic engineeringdc.subject.mesh
TitleGenetische Veränderung von Clostridium ljungdahlii zur Produktion von 1-Butanol aus Synthesegasdc.title
Resource typeDissertationdc.type
DOIhttp://dx.doi.org/10.18725/OPARU-1244dc.identifier.doi
PPN602674255dc.identifier.ppn
URNhttp://nbn-resolving.de/urn:nbn:de:bsz:289-vts-68579dc.identifier.urn
GNDClostridium difficiledc.subject.gnd
GNDSynthesegasdc.subject.gnd
FacultyFakultät für Naturwissenschaftenuulm.affiliationGeneral
Date of activation2009-06-14T23:15:46Zuulm.freischaltungVTS
Peer reviewneinuulm.peerReview
Shelfmark print versionZ: J-H 13.291; W: W-H 11.730uulm.shelfmark
DCMI TypeTextuulm.typeDCMI
VTS-ID6857uulm.vtsID
CategoryPublikationenuulm.category
University Bibliographyjauulm.unibibliographie


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