Human NACHT, LRR, and PYD domain-containing protein 3 (NLRP3) inflammasome activity is regulated by and potentially targetable through Bruton tyrosine kinase

Erstveröffentlichung
2017Authors
Liu, Xiao
Pichulik, Tica
Wolz, Olaf-Oliver
Dang, Truong-Minh
Stutz, Andrea
Wissenschaftlicher Artikel
Published in
Journal of Allergy and Clinical Immunology ; 140 (2017), 4. - S. 1054+. - ISSN 0091-6749. - eISSN 1097-6825
Link to publication
https://dx.doi.org/10.1016/j.jaci.2017.01.017Institutions
UKU. Klinik für Innere Medizin IIIUKU. Klinik für Hals-, Nasen-, Ohrenheilkunde, Kopf- und Halschirurgie
Subject headings
[Free subject headings]: IL-1 | ibrutinib | Bruton tyrosine kinase | NLRP3 | inflammasome | macrophage | X-linked agammaglobulinemia | Staphylococcus aureus | Muckle-Wells syndrome | inflammation | chronic lymphocytic-leukemia | mass-spectrometry | b-cell | nalp3 inflammasome | in-vivo | btk | activation | immunity | expression[DDC subject group]: DDC 610 / Medicine & health