Complement receptors C5aR1 and C5aR2 act differentially during the early immune response after bone fracture but are similarly involved in bone repair

Erstveröffentlichung
2017
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Wissenschaftlicher Artikel

Authors
Kovtun, Anna
Bergdolt, Stephanie
Haegele, Yvonne
Matthes, Rebekka
Lambris, John D.
et al.
Institutions
UKU. Institut für Unfallchirurgische Forschung und Biomechanik
UKU. Institut für Klinische und Experimentelle Trauma-Immunologie
Published in
Scientific Reports ; 7 (2017). - Art.-Nr. 14061. - ISSN 2045-2322
Link to publication
https://dx.doi.org/10.1038/s41598-017-14444-3
Funding information
National Institutes of Health [P01-AI068730]
German Research Foundation as a part of the Clinical Research Unit [KFO200, IG-18/14-2]
Collaborative Research Center [CRC1149, INST 40/491-1]
Keywords
blunt chest trauma; osteoclast differentiation; c5l2; c3a; cells; mice; anaphylatoxins; inflammation; expression; il-1-beta
Dewey Decimal Group
DDC 610 / Medicine & health
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