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Loss of cooperativity of secreted CD40L and increased dose-response to IL4 on CLL cell viability correlates with enhanced activation of NF-kB and STAT6

Wissenschaftlicher Artikel

Bhattacharya, Nupur; Reichenzeller, Michaela; Caudron-Herger, Maiwen; Haebe, Sarah; Brady, Nathan; Diener, Susanne; Nothing, Maria; Döhner, Hartmut; Stilgenbauer, Stephan; Rippe, Karsten; Mertens, Daniel (Universität Ulm, 2015)

Leukemic progenitor cells are susceptible to targeting by stimulated cytotoxic T cells against immunogenic leukemia-associated antigens

Wissenschaftlicher Artikel

Schneider, Vanessa; Zhang, Lu; Rojewski, Markus; Fekete, Natalie; Schrezenmeier, Hubert; Erle, Alexander; Bullinger, Lars; Hofmann, Susanne; Goetz, Marlies; Doehner, Konstanze; Ihme, Susann; Döhner, Hartmut; Buske, Christian; Feuring-Buske, Michaela; Greiner, Jochen (Universität Ulm, 2015)

A phase I/II study of sunitinib and intensive chemotherapy in patients over 60 years of age with acute myeloid leukaemia and activating FLT3 mutations

Wissenschaftlicher Artikel

Fiedler, Walter; Kayser, Sabine; Kebenko, Maxim; Janning, Melanie; Krauter, Juergen; Schittenhelm, Marcus; Goetze, Katharina; Weber, Daniela; Goehring, Gudrun; Teleanu, Veronica; Thol, Felicitas; Heuser, Michael; Doehner, Konstanze; Ganser, Arnold; Döhner, Hartmut; Schlenk, Richard F. (Universität Ulm, 2015)

Mutational spectrum of myeloid malignancies with inv(3)/t(3;3) reveals a predominant involvement of RAS/RTK signaling pathways

Wissenschaftlicher Artikel

Groeschel, Stefan; Sanders, Mathijs A.; Hoogenboezem, Remco; Zeilemaker, Annelieke; Havermans, Marije; Erpelinck, Claudia; Bindels, Eric M. J.; Beverloo, H. Berna; Döhner, Hartmut; Loewenberg, Bob; Doehner, Konstanze; Delwel, Ruud; Valk, Peter J. M. (Universität Ulm, 2015)

International phase 3 study of azacitidine vs conventional care regimens in older patients with newly diagnosed AML with >30% blasts

Wissenschaftlicher Artikel

Dombret, Herve; Seymour, John F.; Butrym, Aleksandra; Wierzbowska, Agnieszka; Selleslag, Dominik; Jang, Jun Ho; Kumar, Rajat; Cavenagh, James; Schuh, Andre C.; Candoni, Anna; Recher, Christian; Sandhu, Irwindeep; Bernal del Castillo, Teresa; Al-Ali, Haifa Kathrin; Martinelli, Giovanni; Falantes, Jose; Noppeney, Richard; Stone, Richard M.; Minden, Mark D.; McIntyre, Heidi; et al. (Universität Ulm, 2015)

Clinical and functional implications of microRNA mutations in a cohort of 935 patients with myelodysplastic syndromes and acute myeloid leukemia

Wissenschaftlicher Artikel

Thol, Felicitas; Scherr, Michaela; Kirchner, Aylin; Shahswar, Rabia; Battmer, Karin; Kade, Sofia; Chaturvedi, Anuhar; Koenecke, Christian; Stadler, Michael; Platzbecker, Uwe; Thiede, Christian; Schroeder, Thomas; Kobbe, Guido; Bug, Gesine; Ottmann, Oliver; Hofmann, Wolf-Karsten; Kroeger, Nicolaus; Fiedler, Walter; Schlenk, Richard; Doehner, Konstanze; et al. (Universität Ulm, 2015)

Outcome of advanced chronic lymphocytic leukemia following different first-line and relapse therapies: a meta-analysis of five prospective trials by the German CLL Study Group (GCLLSG)

Wissenschaftlicher Artikel

Cramer, Paula; Isfort, Susanne; Bahlo, Jasmin; Stilgenbauer, Stephan; Döhner, Hartmut; Bergmann, Manuela; Stauch, Martina; Kneba, Michael; Lange, Elisabeth; Langerbeins, Petra; Pflug, Natali; Kovacs, Gabor; Goede, Valentin; Fink, Anna-Maria; Elter, Thomas; Fischer, Kirsten; Wendtner, Clemens-Martin; Hallek, Michael; Eichhorst, Barbara (Universität Ulm, 2015)

Mutations driving CLL and their evolution in progression and relapse

Wissenschaftlicher Artikel

Landau, Dan A.; Tausch, Eugen; Taylor-Weiner, Amaro N.; Stewart, Chip; Reiter, Johannes G.; Bahlo, Jasmin; Kluth, Sandra; Bozic, Ivana; Lawrence, Mike; Boettcher, Sebastian; Carter, Scott L.; Cibulskis, Kristian; Mertens, Daniel; Sougnez, Carrie L.; Rosenberg, Mara; Hess, Julian M.; Edelmann, Jennifer; Kless, Sabrina; Kneba, Michael; Ritgen, Matthias; et al. (Universität Ulm, 2015)

MicroRNA-223 dose levels fine tune proliferation and differentiation in human cord blood progenitors and acute myeloid leukemia

Wissenschaftlicher Artikel

Gentner, Bernhard; Pochert, Nicole; Rouhi, Arefeh; Boccalatte, Francesco; Plati, Tiziana; Berg, Tobias; Sun, Su Ming; Mah, Sarah M.; Mirkovic-Hoesle, Milijana; Ruschmann, Jens; Muranyi, Andrew; Leierseder, Simon; Argiropoulos, Bob; Starczynowski, Daniel T.; Karsan, Aly; Heuser, Michael; Hogge, Donna; Camargo, Fernando D.; Engelhardt, Stefan; Döhner, Hartmut; et al. (Universität Ulm, 2015)

Acute Myeloid Leukemia

Wissenschaftlicher Artikel

Döhner, Hartmut; Weisdorf, Daniel J.; Bloomfield, Clara D. (Universität Ulm, 2015)

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