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Analysis of regulatory mechanisms governing aromatic compound degradation in Acinetobacter baylyi
Dissertation
The ability to adapt gene expression is a powerful tool of an organism exposed to a continuously changing environment. For example, the mechanisms responsible for the adaptation of bacteria to the continuously changing ...
Characterization of the spontaneous ataxia phenotype in the HCN-ex3/-ex3 mouse line
Dissertation
Transgenic mouse lines were generated by pronucleus injection of a mini-gene. Upon aging one founder line developed an ataxia phenotype although the transgene expression system was inactive. Therefore, the question was ...
Die Rolle negativer Phosphorylierungen in der Regulation klassischer NF-kappaB-Signalwege
Dissertation
The classical NF-kappaB-signaling is not only one uniform pathway but consists of several distinct signaling pathways which differ regarding their inducing agents, the intracellular proteins involved in signal transmission, ...
Quantum optics experiments in a microstructured ion trap
Dissertation
This dissertation describes a prototype experiment aiming at the realization of scalable quantum information. The essential feature is the usage of a novel microstructured ion trap derived from the Paul trap. It allows for ...
Mechanistische Untersuchung und Modellierung der Anodenreaktion in der Karbonat-Brennstoffzelle
Dissertation
Considering distributed energy generation, molten carbonate fuel cells (MCFCs) have best prospects to fulfil the demands of the highly competing energy market. To establish MCFC technology in the market, various requirements ...
MAPKAPK2-Deletion führt zur partiellen Normalisierung des sekretorischen Phänotypen in Telomer-dysfunktionellen Mäusen ohne Auswirkung auf Organerhalt und Überleben
Dissertation
With successive telomere shortening late generation Telomerase knockout mice prematurely develop aging symptoms like a senescence-associated secretory phenotype, myeloproliferation, reduced body weight, crypt atrophy in ...
Cavity-Ring-Down-Spektroskopie als nachweisstarke Detektionsmethode in analytischen Fließsystemen
Dissertation
Over the last decades, numerous developments in the field of standard separation sciences as well as in bioanalytics and biosensor technology have resulted in micro and nanoliter detection volumes. This has motivated the ...
Strukturbildung und optische Eigenschaften von Hybrid-Nanomaterialien synthetisiert via Miniemulsionspolymerisation
Dissertation
The versatility of the miniemulsion technique for the synthesis of hybrid-nanomaterials with different properties is presented.
By using this process it is possible to prepare structured metal-containing hybrid-nanomaterials. ...
Propionibacterium acnes: Einfluss von Lipiden und aktiven Inhaltsstoffen auf Wachstum und Expression von Pathogenitätsfaktoren sowie Konstruktion von Deletionsmutanten
Dissertation
Das Genom von P. acnes KPA171202 (DSMZ16379) ist seit 2004 vollständig sequenziert (Brüggemann et al., 2004). Das vollständig sequenzierte Genom eröffnet nun die Möglichkeit, potentielle Pathogenitätsfaktoren zu identifizieren. ...
Erweiterung des Oszillationsspektrums kommerzieller Rheometer in den Hochfrequenzbereich, an derselben Probe, durch Integration des PRV
Dissertation
Rheometers are the usual equipment to determine viscoelastic behaviour of materials. One of the various methods used in rheometers is the so called frequency-sweep, which means the application of an oscillating excitation ...